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ea0099p32 | Adrenal and Cardiovascular Endocrinology | ECE2024

Physical activity after planned cessation of prednisolone treatment in patients with polymyalgia rheumatica and/or giant cell arteritis: baseline data from the double edge-replace study

Stankovic Jelena , Lund MarieLouise , Dreyer AnjaFenger , Al-Jorani Hajir , Boesen Victor Brun , Borresen StinaWillemoes , Christensen LouiseLehmann , Feldt-Rasmussen Ulla , Glintborg Dorte , Hansen Simon Boggild , Jensen Richard Christian , Jorgensen NannaThurmann , Bislev LiseSofie , Tei Randi , Andersen Marianne , Jorgensen JensOtto

Introduction: Myopathy is a known and dreaded adverse effect of pharmacological glucocorticoid (GC) treatment, but its impact on daily physical activity is not known.Aim: To measure spontaneous physical activity and musculoskeletal function in patients shortly after planned cessation of long-term (>12 weeks) prednisolone treatment.Patients and methods: Baseline data from an ongoing nation-wide prospective study (DOUBLE EDGE &#1...

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ea0099p12 | Adrenal and Cardiovascular Endocrinology | ECE2024

How to assess adrenal function during low dose prednisolone treatment – impact of a 1- vs 2-day prednisolone pause before the ACTH test: Results from the Double Edge-Rescue Study

Willemoes Borresen Stina , Hansen SimonBoggild , Al-Jorani Hajir , Bislev LiseSofie , Boesen VictorBrun , Christensen LouiseLehmann , Feldt-Rasmussen Ulla , Dreyer AnjaFenger , Glintborg Dorte , Jensen RichardChristian , Jorgensen NannaThurmann , Lund MarieLouise , Okutan Sema , Stankovic Jelena , Tei Randi , Hetland MereteLund , Locht Henning , Hauge Ellen , Keller Kresten , Just SorenAndreas , Voss Anne , Sorensen Henrik Toft , Stewart Paul M. , Jorgensen JensOtto , Andersen Marianne , Klose Marianne

Background: Correctly identifying glucocorticoid-induced adrenal insufficiency in patients tapering prednisolone treatment to ≤5 mg daily is crucial. Pausing prednisolone before an ACTH-test is standard, yet the optimal pause duration is uncertain.Aim: To determine the outcome of an ACTH-test after 1 vs 2 days prednisolone pause before the test.Methods: Baseline data from an ongoing randomised clinical trial (EudraCT:20...

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Endocrine Abstracts

Physical activity after planned cessation of prednisolone treatment in patients with polymyalgia rheumatica and/or giant cell arteritis: baseline data from the double edge-replace study

How to assess adrenal function during low dose prednisolone treatment – impact of a 1- vs 2-day prednisolone pause before the ACTH test: Results from the Double Edge-Rescue Study

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